K2VITAL™ – Science Done Right.
Big in Numbers. Bigger in Meaning.
The Evidence
Speaks.
Leadership in vitamin K2 science is not defined by study count alone. It is defined by the quality, scale and relevance of the evidence behind it. K2VITAL™ turns scientific complexity into clarity. The numbers reveal the research and commitment behind the trust.
Everyone Claims it.
We Prove it.
Our continued commitment to clinical research sends a clear message: With 8 ongoing trials as of 2026, K2VITAL™ has ranked #1 as the most extensively studied vitamin K2 (MK-7) since 2021 — and we’re not stopping there.
Not by Claims.
By Results.
That’s why K2VITAL™ is consistently used in large-scale clinical trials with 300+ participants per trialand long-term studies spanning 2+ years. K2VITAL is shaping the global vitamin K2 research.
Facts over Fiction.
Evidence Wins.
Tested in 13 double-blind, placebo-controlled studies, this evidence provides a robust foundation for scientific confidence. Since 2021, our trials had more participants than all other vitamin K2 manufacturers combined.
The Evidence Behind the Numbers
Every number highlighted above reflects years of scientific investment, collaboration and clinical research.
Numbers alone do not tell the whole story. Their meaning comes from the research behind them. From ongoing clinical trials and large-scale studies to rigorous study designs, the evidence below brings the numbers to life.
Explore the studies that contribute to K2VITAL™’s growing body of evidence.
Ranked #1
Ranked #1 as the most clinically studied vitamin K2 (MK-7) since 2021 and of those, 8 clinical studies are still ongoing as of 2026:
- MIC – Menaquinone in Children, checking Vitamin K2-Mk7 supplementation absorption and health effects in healthy children and adolescents.
- The DANish COronary DEcalcification (DANCODE) Trial
- The InterVitaminK Trial – Effects of Vitamin K Supplementation on Cardiovascular, Metabolic, and Bone Health
- Vitamin K2 and Muscle Weakness in Type 2 Diabetes
- Vitamin K2 Supplements for Muscle Recovery
- The use of vitamin K2 in Parkinson’s Disease patients with mitochondrial dysfunction: A theranostic, proof-of-concept, placebo- controlled trial in a parallel group design
- Antioxidant and Immune Effects of Vitamin K2
- Bioavailability of Different Vitamin K Vitamers Studied Using 13C-labelled Vitamin K Vitamers (BioMicro)
300+ participants
300+ participants in the following large-scale clinical trials and long-term studies spanning 2+ years:
Tested in 13 studies
Tested in 13 studies designed as double-bind, placebo-controlled trials:
- MIC – Menaquinone in Children, checking Vitamin K2-Mk7 supplementation absorption and health effects in healthy children and adolescents
- The DANish COronary DEcalcification (DANCODE) Trial
- The InterVitaminK Trial – Effects of Vitamin K Supplementation on Cardiovascular, Metabolic, and Bone Health
- Vitamin K2 and Muscle Weakness in Type 2 Diabetes
- Antioxidant and Immune Effects of Vitamin K2
- The viTAmin K2 and rEcOVery from ExeRcise (TAKEOVER)
- Vitamin K2 Supplements for Muscle Recovery
- Randomized Controlled Clinical Trial to Investigate Effects of Vitamin K2 in COVID-19
- Placebo-controlled double-blind randomized controlled trial investigating vitamin K supplementation on vascular calcification propensity in vitamin K deficient renal transplant recipients
- The use of vitamin K2 in Parkinson’s Disease patients with mitochondrial dysfunction: A theranostic, proof-of-concept, placebo- controlled trial in a parallel group design
- The Aortic Valve DECalcification (AVADEC) Trial
- Effect of Vitamin K2 (MK7) on Cardiovascular and Bone Disease in Dialysis Patients
- Bioavailability and Chemical/Functional Aspects of Synthetic MK-7 vs Fermentation-Derived MK-7 in Randomised Controlled Trials
K2VITAL™ is Vitamin K2 done right.
K2VITAL™ is a patented, typically 99.8% all-trans MK-7 vitamin K2, identical to the naturally occurring, bioactive form. It supports calcium metabolism by activating vitamin K-dependent proteins, helping direct calcium to where it’s needed most for healthy bones and cardiovascular health.