K2VITAL™

K2VITAL™ offers uncompromising quality and stability, providing the maximum health benefits of vitamin K2.

K2VITAL™ is patented, typically 99.7% all-trans K2 MK-7. Identical to the K2 molecule found in nature and fully bioactive.

Vitamin K2 all-trans MK-7 is the biologically active form of vitamin K2, a fat-soluble vital vitamin that supports calcium metabolism.

Vitamin K2 activates vitamin K-dependent proteins which help move calcium to where it needs to be in the body, supporting bone and heart.

All-trans matters

In nature, menaquinones are found in a linear configuration, called trans isomers.

This is what’s known as the most bioactive form, and it is the key to activating K-dependent proteins.

However, due to inferior production methods or stability issues, these menaquinones can take on a non-linear, cis shape.

These cis isomers are not as biologically effective.

K2 Research Network

Unmasking the Truth

Misleading labels exposed by Balchem – Our deep commitment to quality and excellence has led us to develop a pioneering report, investigating how many supplements out there are not living up to their labels.

Key Findings:

• 71% of K2 supplements fail quality standards.
• Excessive cis isomers lower efficacy
• Many formulations degrade rapidly, compromising quality.

At Balchem, we aim to raise awareness and set new industry standards. Our K2VITAL^TM offers unmatched exceptional stability and exceptional purity.

About K2VITAL™

K2VITAL™ is exceptionally pure Vitamin K2 MK-7 in its bioactive all-trans form.

The once forgotten vitamin is an essential nutrient directing calcium away from the arteries and deposits it into the bone. supporting strong bones and a healthy heart.

K2VITAL™ offers uncompromising quality and stability, providing the maximum benefits of vitamin K2.

Typically 99.7% All-trans

Pure and Stable

Fully Bioactive

50%

Nearly 50% of the US population does not get enough vitamin K in their diet.¹

Black-painted wooden dish, empty and minimalist design

10-25%

Only 10-25% of total vitamin K intake in Europe is from Vitamin K2.^{2, 3}

Molecular structure view with green color

72 Hours

MK-7 remains biologically active in the body – longer than any other form of vitamin K.⁴

Vitamin K is an essential vitamin that’s needed all over the body, at every stage of our lives.

90-120 μg

sufficient daily dose for good bone health.

It’s responsible for activating Vitamin K-depended proteins, helping deposit calcium into the bone.

Fermented foods are primary sources of vitamin K2. Western diets are significantly low in vitamin K2. As such, K2 may be supplemented for optimal bone and heart health.

Populations that reach the recommended daily dose were shown to have better heart and bone health.

Quality that Shakes Up the Industry

Vitamin K2 as MK-7 and only MK-7 in its bioactive all-trans form, identical to the molecule found in nature.

Stability You Can Lean On

K2VITAL™ DELTA offers exceptional stability in finished products with the world’s only patented double-microencapsulated K2 for mineral formulations.

Backed by Masterful Science

K2VITAL™ backed by multiple clinical trials, ahead of the curve, taking a leading role in trailblazing research, uncovering the future of K2.

The K2 Powerhouse

K2VITAL™ offers a 360°-degree service that customers can rely on, a scientifically proven brand, tailored solutions, market intelligence, marketing support and a collaborative support revolutionizing the K2 segment.

Purity takes Honesty

Our production process yields in pristine material: MK-7 as a pure substance.

Our passionate scientists have created pure K2, all-bioactive K2 MK-7, exactly like the vitamin K2 found in nature. The production of K2VITAL™ is based on a pioneering, one-of-a-kind, patented process.

Our preparations feature pure, all-trans MK-7, thoughtfully formulated to conform to the intended dosage with high accuracy, verified by accredited testing methods.

Nourishment for
Every Stage of Life

Nourish your bones, empower your heart at every stage of life. Vitamin K2 helps keep calcium in balance.

Bone Health

o Vitamin K2 activates osteocalcin which plays a role for bone metabolism^{1, 5, 6}

o Vitamin K2 MK-7 helps maintain healthy bone mass^{1, 7-9}

Bone and Joint Health

Heart Health

o Vitamin K2 supports arterial elasticity^{10, 11}

o Vitamin K2 supports a healthy heart^11-16

Heart Health

Women’s Health

o Clinical data demonstrates that vitamin K2 (MK-7) has a role in maintaining healthy bone mass and structure in postmenopausal women.^{1, 7-9}

Women’s Health

Exercise Recovery

o Vitamin K2 (MK-7) may help trained athletes achieve increased cardiac output during aerobic exercise¹⁷

o Vitamin K2 supports ATP production, the source of energy your body’s cells / muscle uses^{18, 19}

Sports

Get in touch

Where to find K2VITAL™

Discover our Winning Formulations

Our formulations concept contains market-ready K2 products backed by consumer research.

We’ve helped hundreds of customers from around the world develop their own innovative formulations in collaboration with industry leaders, harnessing cutting-edge technology and high- quality ingredients. From the spark of an idea to a product launch, we’re here at every step, shortening your development cycle, from months, to weeks, or even days.

Market ready product concepts.

Look for products with the K2VITAL™ logo.

Vital Trio

The Powerful Trio for Essential Health
Supplements K2VITAL™, Vitamin D3,
Chelated Magnesium Bisglycinate.

Vital Trio

1. Jar: K2VITAL D3 Smart Caps
2. Dropper: K2VITAL D3 Smart Drops.

Perfect Pair

Say hello to K2VITAL™, Vitamin D’s perfect
partner K2VITAL™, Vitamin D3.

Get in Touch

K2VITAL™ is Vitamin K2 done right.

It’s proof that our partners and consumers are getting the absolute best this vitamin has to offer. It’s the brand people can count on when they want to make business easier, and live life healthier.

Get in touch

Dominik Mattern, VP Science, Business Development and Marketing speaks on K2Vital

“Through K2VITAL, we are committed to raising the bar for Vitamin K2 MK-7 with uncompromising quality, transparency, science and innovation. ‘Doing it right’ is not just our tagline—it’s our ethos, driving us to elevate standards and shape the future of K2 products.”

— Dominik Mattern, VP Science, Business Development and Marketing

June 13, 2024

Benefits of Vitamin K2 and D3 for Heart Health

Man jogs in gray outfit along waterfront path.

February 1, 2024

New Peer-Reviewed Research Highlights Promising Potential of Vitamin K2 MK-7 for Heart Health

Two black women leaning against a white wall.,

January 16, 2024

TOP 2024 Evolving Trends in Health and Nutrition

References

National Institutes of Health, O.o.D.S.O. Vitamin K – Fact Sheet for Health Professionals. September 25, 2024]; Available from: https://ods.od.nih.gov/factsheets/vitaminK-HealthProfessional/#h3.
Halder, M., et al., Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease. Int J Mol Sci, 2019. 20(4).
Beulens, J.W., et al., The role of menaquinones (vitamin K(2)) in human health. Br J Nutr, 2013. 110(8): p. 1357-68.
Schurgers, L.J., et al., Vitamin K-containing dietary supplements: comparison of synthetic vitamin K1 and natto-derived menaquinone-7. Blood, 2007. 109(8): p. 3279-83.
Theuwissen, E., et al., Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects. Br J Nutr, 2012. 108(9): p. 1652-7.
Mandatori, D., et al., The Dual Role of Vitamin K2 in “Bone-Vascular Crosstalk”: Opposite Effects on Bone Loss and Vascular Calcification. Nutrients, 2021. 13(4).
Zhang, Y., et al., Effect of Low-Dose Vitamin K2 Supplementation on Bone Mineral Density in Middle-Aged and Elderly Chinese: A Randomized Controlled Study. Calcif Tissue Int, 2020.
Knapen, M.H., et al., Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women. Osteoporos Int, 2013. 24(9): p. 2499-507.
Institute of Medicine, P.o.M. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. September 25, 2024]; Available from: https://www.ncbi.nlm.nih.gov/books/NBK222299/.
Knapen, M.H., et al., Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial. Thromb Haemost, 2015. 113(5): p. 1135-44.
Vermeer, C. and H. Vik, Effect of Menaquinone-7 (vitamin K2) on vascular elasticity in healthy subjects: results from a one-year study. Vascul Dis Ther, 2020. 5: p. 1-4.
Hariri, E., et al., Vitamin K(2)-a neglected player in cardiovascular health: a narrative review. Open Heart, 2021. 8(2).
Hasific, S., et al., Effects of Vitamin K2 and D Supplementation on Coronary Artery Disease in Men. JACC: Advances, 2023. 2(9): p. 100643.
Gast, G.C., et al., A high menaquinone intake reduces the incidence of coronary heart disease. Nutr Metab Cardiovasc Dis, 2009. 19(7): p. 504-10.
Haugsgjerd, T.R., et al., Association of dietary vitamin K and risk of coronary heart disease in middle-age adults: the Hordaland Health Study Cohort. BMJ Open, 2020. 10(5): p. e035953.
Geleijnse, J.M., et al., Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. J Nutr, 2004. 134(11): p. 3100-5.
McFarlin, B.K., A.L. Henning, and A.S. Venable, Oral Consumption of Vitamin K2 for 8 Weeks Associated With Increased Maximal Cardiac Output During Exercise. Altern Ther Health Med, 2017. 23(4): p. 26-32.
Vos, M., et al., Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency. Science, 2012. 336(6086): p. 1306-10.
Ronning, S.B., et al., Vitamin K2 improves proliferation and migration of bovine skeletal muscle cells in vitro. PLoS One, 2018. 13(4): p. e0195432.

*These statements have not been evaluated by the US Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.