
Choline for Cognition & Mood
Fuel Your Brain. Elevate Your Mood.
In today’s fast-paced world, cognitive performance and emotional well-being are more important than ever.
Whether you’re an athlete, student, or professional, your brain’s ability to stay sharp and resilient is key to success. Choline is a vital nutrient that supports both cognition and mood—helping you stay focused, balanced, and mentally strong.
The Science Behind Choline’s Cognitive Power
Choline is the building block of acetylcholine, a neurotransmitter essential for:

Memory formation and recall

Sustained focus and attention

Learning and processing new information

Fast signal transmission across brain cells
Acetylcholine Acts as the Brain’s High-Speed Communication Network
Acetylcholine enables neurons to transmit signals efficiently1. Choline also supports the structure of brain cell membranes through phosphatidylcholine1, and together these functions aid optimal cognitive function, cellular protection, and neural communication1.
NIH-funded research has shown that choline is actively transported across the blood-brain barrier by a specialized protein called FLVCR2, underscoring its essential role in brain health2.
Choline’s Role in Brain Health
Choline plays a critical role in brain health and cognitive function:
Supporting Neurotransmitter Balance
Adequate choline intake supports acetylcholine synthesis, which helps to maintain mood regulation1.
Cognitive Function and Memory
Choline contributes to mental clarity by supporting overall cognitive function and helping to maintain a healthy memory1.
Supports Mind / Body Connection
It aids in brain cell communication and helps with muscle control, supporting your performance.

Choline for Lifelong Brain Support
When consumed in adequate amounts, particularly during prenatal development, choline supports:
- Neurogenesis – The creation of new brain cells during early development3
- Synaptic plasticity – The brain’s ability to adapt and learn
- Cognitive performance – Supplementation during pregnancy leads to lasting cognitive improvements, observed as early as the first year of life4 and lasting even at baby’s 7th birthday5
Choline is especially critical during fetal development, where it supports the formation of the hippocampus, a brain region essential for memory 3. But its benefits extend throughout life, helping to maintain cognitive function and emotional regulation as we age.

How to Optimize Choline Intake
Despite its importance, most people don’t get enough choline from diet alone ~9/10 adults in the United States don’t get enough choline in their diet.6
Choline-rich foods include eggs, liver, fish, and certain vegetables, but supplementation is often necessary.
For wellness strategies aimed at supporting cognition and mood, optimizing choline intake is essential. Supplementation with high-quality choline, like VitaCholine®, can help bridge the gap and support peak mental performance.