How Choline Can Support Mood and Brain Health

Posted: January 10, 2024

At Balchem, we recognize the critical role of choline in enhancing brain health and mood stability. Certain nutrients can help support mental health during challenging times, promoting overall well-being. Stay with us for valuable insights and information that will empower you to make informed decisions for your product development.

Choline’s Role in Mood and Brain Health

Choline plays a crucial role in enhancing mood and brain health. Let’s dive into how choline impacts mood regulation, memory, learning, and brain cell communication.

  • Mood Regulation and Choline: Choline is involved in the synthesis of the neurotransmitter acetylcholine, which plays a critical role in mood regulation. Adequate choline intakes are essential for maintaining a proper acetylcholine synthesis, which has an important role in the maintenance of a normal mood. (1, 2)
  • Choline and Memory/Learning: Acetylcholine has multiple important roles, including supporting memory and cognitive function. Adequate choline intake is key to providing proper support for these important functions. (2)
  • Brain Cell Communication and Choline: Choline plays a significant role in facilitating communication between brain cells and throughout the body by supporting the production and release of neurotransmitters. Optimal levels of choline are necessary for efficient signal transmission within the brain and aiding in muscle control, thereby supporting overall brain function. (2)

Understanding Choline: Key Player in Mood and Brain Health

Choline is an essential nutrient that supports our memory, mood, muscle control, and various bodily functions, playing a vital role in the well-being of the brain and nervous system (2). While our bodies can produce limited amounts of choline, we can’t make enough to meet our daily requirements and thus we need to consume choline in the diet to maintain our health (2,3). The main dietary sources of choline in the United States consists primarily of animal-based products that are particularly rich in choline- meat, poultry, fish, dairy products, and eggs (2). Unfortunately, nearly 90% of American adults fall short of the recommended choline intake in their diet (4).

Cognition Boost: The Role of Choline in Mental Processes

Cognition, the foundation of our mental process, is fundamental to our daily lives. Choline has been recognized for its role in cognitive function (4). It serves as a precursor to acetylcholine, a neurotransmitter essential for memory, regulation of mood, and supporting attention. (2, 4) Clinical trials have even demonstrated its ability to improve cognitive performance. (5)

Optimizing Choline Intake for Enhanced Mood and Brain Health

For products and wellness strategies aimed at supporting mood and brain health, optimizing choline intake is essential. Here are some tips to consider:

  • Balancing choline intake: Choline can be obtained naturally from various foods like eggs, liver, fish, and certain vegetables. Incorporating these choline-rich ingredients in your products can naturally boost choline levels. In addition, considering choline supplementation can be beneficial, especially if your target consumers’ diets are lacking in choline-rich foods. (2)
  • Lifestyle factors: Don’t forget about the basics – like regular exercise, adequate sleep, and stress management techniques that can all contribute to your overall health and well-being.
  • Personalized advice: Each individual’s choline needs may vary based on factors such as age, sex, and overall health. Providing personalized advice tailored to your consumers’ specific needs can help guide them towards maintaining optimal mood and brain health.

VitaCholine®: Supercharge your Body and Mind

VitaCholine® is a key player in brain health. (4) Its dynamic function contributes to supporting the production of acetylcholine, a neurotransmitter that is essential for regulating our mood, especially on challenging days. (1,2) VitaCholine® is an essential part of a well-balanced diet to help promote your overall wellness.

Our Commitment to Your Holistic Well-Being: A Journey of Support

At Balchem Corporation, we’re not just providing solutions; we’re curating experiences that elevate your entire well-being. From our award-winning VitaCholine® to our family of Albion® Minerals, Balchem offers multiple innovative nutritional options to help consumers support a healthy mood across various application formats and business segments.

Looking for more valuable information on how VitaCholine® can meet the rising demand for cognitive health supplements? Click the link below to read our latest Press Release covering the topic of how we are expanding production to meet the rising demand for cognitive health supplements (


1) Dulawa, S. C., & Janowsky, D. S. (2019). Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. Molecular psychiatry, 24(5), 694–709.

2) Choline – Health Professional Fact Sheet (

3) Choline – Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline – NCBI Bookshelf (

4) USDA, Agricultural Research Service, 2023. Usual Nutrient Intake from Food and Beverages, by Gender and Age, What We Eat in America, NHANES 2017-March 2020 Prepandemic. Available at:

5) Naber M, et al., Sci Rep 2015; 5: 13188.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Schedule Now

Fill out the form below, and we will be in touch shortly.

Contact Information
Who would you like to speak with?

Sign up for updates!

Click below to sign up to receive our monthly newsletter, the Balchem Beat.